Hematopathology & Cytopathology International Cases🇺🇳

Author: Najmaldin Saki(Ph.D); Kimia Vaezi(M.Sc) Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Normal basophil   Published Date: 03/20/2026 Peripheral blood smear examination in a patient with chronic myeloid leukemia (CML) demonstrates a basophil. https://imagebank.hematology.org/image/66299/basophil2?type=upload

Author: Najmaldin saki(Ph.D); Kimia Vaezi(M.Sc) Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of platelets (cross-reference with specific diagnoses when appropriate > Large and giant platelets   Published Date: 03/20/2026 In the peripheral blood smear of a patient with thrombocytosis, normal, giant, and large platelets were observed from left to right, respectively. https://imagebank.hematology.org/image/66297/giant-platelet-in-a-patient-with-thrombocytosis?type=upload

Author: Najmaldin Saki (Ph.D); Kimia Vaezi (M.Sc) Category: Laboratory Hematology Published Date: 02/26/2026 Giant Platelets are typically larger than 7 micrometers in diameter. That can be a sign of underlying genetic disorders. These disorders are often associated with low Platelets count and a need a manual blood smear examination. using Wright_Giemsa staining. https://imagebank.hematology.org/image/65949/giant-platelets-2?type=upload

Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Chronic Myelogenous Leukemia (CML), BCR-ABL1+ Published Date: 02/26/2026 The Peripheral blood smaer in chronic myeloid leukemia(CML) demonstrating a broad spectrum of myeloid cells at different stages of differentiation.Identified cells include: The upper cell represents a myeloblast, whereas the lower cell represents a myelocyte. https://imagebank.hematology.org/image/66138/cml2?type=upload

Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Promyelocyte Published Date: 02/26/2026 The Wright-Giemsa-stained peripheral blood smear reveals the presence of promyelocyte. https://imagebank.hematology.org/image/66143/promyelocyte?type=upload

Author: Najmaldin Saki (Ph.D); Kimia Vaezi (M.Sc) Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Chronic Myelogenous Leukemia (CML), BCR-ABL1+ Published Date: 02/26/2026 Blast cell with a prominent nucleolus in a patient with chronic myeloid leukemia(CML). https://imagebank.hematology.org/image/66282/cml?type=upload

Author: Najmaldin Saki (Ph.D); Kimia Vaezi (M.Sc) Category: Laboratory Hematology Published Date: 02/19/2026 Giant Platelets are significantly larger than normal Platelets and even larger than red blood cells.Giant Platelets are often linked to inherited disorders such as:Bernard_soulier syndrome  They can also be seen in conditions like myeloproliferative neoplasms,myelodysplasia,and some forms of immune thrombocytopenia.   https://imagebank.hematology.org/image/65948/giant-platelets?type=upload

Author: Najmaldin Saki (Ph.D); Kimia Vaezi (M.Sc) Category: Laboratory Hematology Published Date: 02/19/2026 Here we present a case of patient with large Platelets in her peripheral blood smear.using Wright-Giemsa staining https://imagebank.hematology.org/image/65947/large-platelets?type=upload

Hypersegmented Neutrophils in Peripheral Blood Smear Image ID: 66291 Authors: Najmaldin Saki, Ph.D, FCLS; Kiana Nemovi, M.Sc; Amirhossein Mohammadzadeh, M.Sc Description: Peripheral blood smear showing two hypersegmented neutrophils with markedly lobulated nuclei. Nuclear chromatin is condensed, and cytoplasmic morphology is well-preserved. This image demonstrates abnormal nuclear segmentation without reference to any underlying disorder.

Macro‑ovalocyte 1 Image ID: 66113 Author: Najmaldin Saki, Ph.D, FCLS; Amirhossein Mohammadzadeh, M.Sc Published Date: 01/22/2026 Description: Peripheral blood smear showing megaloblastic change despite a normal MCV. Scattered macro‑ovalocytes, for example those indicated by arrows, demonstrate classic features of impaired DNA synthesis. Source: https://imagebank.hematology.org/image/66113/macroovalocyte-1?type=upload

Eosinophil Author: Najmaldin Saki, Ph.D; Kimia Vaezi, M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells Published Date: 01/22/2026 Normal eosinophil. https://imagebank.hematology.org/image/66087/eosinophil?type=upload

Hypersegmented neutrophil Author: Najmaldin Saki, Ph.D; Kimia Vaezi, M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Hypersegmented neutrophil Published Date: 01/22/2026 Hypersegmented neutrophil. https://imagebank.hematology.org/image/66086/hypersegmented-neutrophil?type=upload

Basophil Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Normal basophil Published Date: 01/22/2026 A basophil was identified in the peripheral blood smear.Basophils are granulocytic leukocytes characterized by large,coarse basophilic granules that often obscure the nucleus. https://imagebank.hematology.org/image/66137/basophil?type=upload

Eosinophilic Myelocyte Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells Published Date: 01/22/2026 The peripheral blood smear examination revealed the presence of eosinophilic myelocyte.This cell was characterized by a around or oval nucleus lying eccentrically.The granules in the cytoplasm are clearly light purple/pink in color. https://imagebank.hematology.org/image/66148/eosinophilic-myelocyte?type=upload

Neutrophil Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Normal neutrophil   Published Date: 01/22/2026 The peripheral blood smear examination reveals the presence of neutrophils in the setting of acute myeloid leukemia(AML). https://imagebank.hematology.org/image/66140/neutrophil?type=upload

Hypersegmented Neutrophil in a Patient with Thrombocytosis Author: Najmaldin Saki,Ph.D; Kimia Vaezi,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Hypersegmented neutrophil Published Date: 01/22/2026 The peripheral blood smear shows thrombocytosis with hypersegmented neutrophils. https://imagebank.hematology.org/image/66139/hypersegmented-neutrophil-in-a-patient-with-thrombocytosis?type=upload

NRBC Author: Najmaldin Saki, Ph.D; Kimia Vaezi, M.Sc Category: Laboratory Hematology > Basic cell morphology > Red cell inclusions and abnormalities > Nucleated Red Blood Cell Published Date: 01/22/2026 An orthochromatic erythroblast has a round, dark nucleus with an almost absent/uniform chromatin pattern. The nucleus is dying and will be expelled from the cell in the next maturation step. https://imagebank.hematology.org/image/66085/nrbc?type=upload

Auer rod in AML Author: Najmaldin Saki ,Ph.D; Kimia Vaezi ,M.Sc Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Leukemic myeloblast with Auer rod   Published Date: 01/22/2026 Peripheral blood smear of a patient diagnosed with Acute Myeloid Leukemia(AML)shows auer rod in myeloid blast cell.Auer rods are red/pink colored, rod-shaped cytoplasmic inclusions that occur only in cells of the myeloid lineage. https://imagebank.hematology.org/image/66084/auer-rod-in-aml?type=upload

Basophilic Myelocyte Image ID: 66051 Author: Najmaldin Saki, Ph.D, FCLS; Amirhossein Mohammadzadeh, M.Sc; Kiana Nemovi, M.Sc Published Date: 12/19/2025 Description: Peripheral blood smear from a patient with BCR‑ABL1–positive chronic myeloid leukemia showing a basophilic myelocyte (right) with dense, coarse, dark basophilic granules partially obscuring the nucleus. A myelocyte (left) with an oval nucleus, fine chromatin, and pale cytoplasm lacking prominent granulation is also present. Expansion of basophil precursors is a characteristic finding in chronic‑phase CML. Source: https://imagebank.hematology.org/image/66051/basophilic-myelocyte

Giant Platelet Image ID: 66029 Author: Najmaldin Saki, PhD, FCLS; Amirhossein Mohammadzadeh M.Sc; Fatemeh Shirmardi M.Sc Published Date: 12/04/2025 Description: Peripheral blood smear from a healthy individual showing a giant platelet. Occasional large platelets may be observed in normal individuals. Wright–Giemsa stain, ×1000 Source: https://imagebank.hematology.org/image/66029/giant-platelet