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https://oralcareexpertt.blogspot.com/2026/05/local-anesthetic-techniques-drug.html
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Because of massive reports on group , some are unable to access , please vait for some days more ! The issue will automatically resolve
The Great Indian House Wife Killer, SuperVasmol Keshkala is extensively used by Rural Indian housewives as a Hair colour and also as a time tested beverage for difficult times. It is Easy to purchase and inexpensive, The “Herbal, Ammonia free” ingredients make it a familiar home shelf product. In my previous ER alone we received atleast 10-15 cases each year (case Images attached). Almost everyone brought with significant consumption will present with Hypoxic Cardiac arrest and Diffuse Cervicolaryngeal Edema making Intubation or Cricothyroidotomy impossible, requiring Emergency Tracheostomy during CPR. We even had Covid positive patients brought with Vasmol poisoning. The main culprit compound is Paraphenylenediamine (PPD). Classic presentation includes Angioneurotic edema of face and neck with hoarseness of voice and stridor, rhabdomyolysis with dark brown colored urine and acute kidney injury (AKI). (Image attached) Treatment include securing the Airway, early gastric lavage, Forced Alkaline Diuresis, Hemoperfusion / Dialysis (PPD is non dialyzable), steroids and antihistamines (management of airway edema), fluid resuscitation and vasopressor therapy when needed. We have proposed to study the Role of Nebulized Epinephrine in Hairdye poisoning as it was proven to be efficacious in reducing the laryngeal edema of Croup, however the study was abandoned. PPD is banned in countries like Germany, France, Sweden, Sudan but available in the store nextdoor in India. Many Indian Toxicologists and Medical leaders have written letters to Vasmol to remove PPD from their product. Our recognition and debate on this issue might bring about some change and highlight the deaths of gullible rural populations, susceptible to this poison.
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ELECTROLYTES What are electrolytes ! Electrolytes are substances that have a natural positive or negative electrical charge when dissolved in water. An adult's body is about 60% water, which means nearly every fluid and cell in your body contains electrolytes. They help your body regulate chemical reactions, maintain the balance between fluids inside and outside your cells, and more. Importance of electrolytes These electrolytes are essential to various bodily functions and an electrolyte imbalance can be dangerous and even life threatening, depending on the clinical scenario. The balance of electrolyte levels is therefore carefully maintained in the body and may be checked in the blood or urine as a measure of health. This complex and subtle balance needs to be maintained between the intracellular and extracellular environments. In particular, the osmotic gradient of electrolytes must be carefully maintained in order to ensure a healthy blood pH and an adequate level of hydration, factors that are essential for the proper function of muscles and nerves. Several mechanisms exist to help regulate the electrolyte concentration in the body. Muscles and nerves are both stimulated by the activity of electrolytes in the intracellular, extracellular and interstitial fluid. Ion channels exist on the surface of the cell membrane to transport electrolytes to and from the cell. For instance, muscle contraction depends on the presence of potassium, calcium and sodium ions and insufficient levels of these ions may lead to muscle weakness or spasms. If an electrolyte imbalance has been caused by electrolyte loss through diarrhea or vomiting, for example, an oral rehydration solution (ORS) containing electrolytes and fluids can be used to replenish the body. In severe cases of electrolyte loss, an intravenous (IV) route of administration may be necessary. A severe electrolyte imbalance can cause neurological and cardiac complications and may be fatal if not recognised and treated promptly.
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NEET :- UG
Big News for Dental Students! 🦷✨ The Dental National Exit Test (NExT-Dental) is coming soon! 🔑 Key Highlights: ✅ Mandatory for Licensure – Every BDS graduate must pass to practice dentistry in 🇮🇳. ✅ MDS Admissions – Replaces NEET MDS for PG seats. ✅ Structure – Theory + Clinical Skills for comprehensive assessment. ✅ Implementation – Rolling out within 3 years of the National Dental Commission Bill 2023.
In new delhi , yeah but if u are from other part of India , then u have to manage pg , or rents also from that salary ,,👍 if u Ready to manage all these then dm me , I will arrange job for u
Mastering emergency medication protocols can save lives! 🚑 1. Epinephrine Drug Class: Alpha/Beta Adrenergic Agonist 🔴Uses: - Ventricular fibrillation (VF) / Pulseless Ventricular Tachycardia (VT) - Symptomatic bradycardia - Anaphylaxis - Asystole / Pulseless Electrical Activity (PEA) 🔴Pathophysiology: Stimulates alpha and beta-adrenergic receptors to relax heart and lung smooth muscles and dilate blood vessels, increasing heart rate and blood pressure. 🔴Dosing: - VF/PEA/Asystole: 1 mg IV/IO every 3–5 minutes - Symptomatic Bradycardia: Infusion at 2–10 mcg/min, titrating to response 2. Atropine Drug Class: Anticholinergic 🟣Uses: - Bradycardia - Pre-surgical reduction of saliva and respiratory secretions 🟣Pathophysiology: Blocks acetylcholine at parasympathetic sites in smooth muscle, increasing heart rate. 🟣Dosing: 1 mg IV/IO every 3–5 minutes (maximum: 3 mg) 3. Amiodarone Drug Class: Antiarrhythmic 🟡Uses: - Ventricular fibrillation (VF) / Pulseless Ventricular Tachycardia (VT) - Recurrent, hemodynamically unstable VT 🟡Pathophysiology: Blocks potassium channels, reducing abnormal electrical activity in the heart. This slows conduction and restores normal rhythm. 🟡Dosing: - First dose: 300 mg IV/IO push - Second dose: 150 mg IV/IO push 4. Adenosine Drug Class: Antiarrhythmic 🟢Uses: - Supraventricular Tachycardia (SVT) not resolved by vagal maneuvers 🟢Pathophysiology: Temporarily blocks AV node conduction, interrupting reentrant circuits causing SVT. 🟢Dosing: - First dose: 6 mg IV/IO rapid push over 1–3 seconds, followed by 20 mL saline flush - Second dose: 12 mg IV/IO rapid push 5. Calcium Chloride Drug Class: Electrolyte 🔵Uses: - Cardiac arrest - Hyperkalemia - Hypocalcemia 🔵Pathophysiology: Enhances contraction of muscles and cardiac function by increasing calcium availability. 🔵Dosing: - In cardiac arrest: 20 mg/kg IV/IO bolus - Non-arrest: Infuse over 30–60 minutes 6. Sodium Bicarbonate Drug Class: Alkalinizing Agent 🟤Uses: - Tricyclic antidepressant overdose - Metabolic acidosis in cardiac arrest - Hyperkalemia-related cardiac arrest 🟤Pathophysiology: Neutralizes excess acid in the blood, correcting acidosis and improving heart function. 🟤Dosing: 1 mEq/kg IV push in a dose of 50 mL D5W 7. Magnesium Sulfate Drug Class: Antiarrhythmic and Electrolyte ⚪Uses: - Torsades de pointes (a type of polymorphic VT) - Arrhythmias due to hypomagnesemia ⚪Pathophysiology: Slows down calcium influx into the SA node, stabilizing the heart's rhythm. 8. Lidocaine Drug Class: Antiarrhythmic ⚫Uses: - Ventricular fibrillation (VF) - Pulseless Ventricular Tachycardia (VT) - Local anesthesia ⚫Pathophysiology: Blocks sodium influx into cardiac cells, stabilizing their electrical activity and reducing excitability. ⚫Dosing: 1–1.5 mg/kg IV push, repeated every 5–10 minutes as needed
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