Psychiatry Updates

Adolescent alcohol exposure disrupts astrocyte-synaptic structural and functional coupling in the male dorsal hippocampus https://www.nature.com/articles/s41380-026-03817-8

Neurabin I haploinsufficiency disrupts ion channel regulation and synaptic maturation in human cortical neurons in neurodevelopmental disorders https://www.nature.com/articles/s41380-026-03818-7

Glial-neuronal crosstalk via GABA signaling: mechanistic insights into neuropsychiatric and neurological pathophysiology https://www.nature.com/articles/s41380-026-03819-6

Genetic clusters of BMI reveal symptom-specific causal effects on depression https://www.nature.com/articles/s41380-026-03830-x

[Articles] Inequalities in mortality following SARS-CoV-2 infection for people with severe mental illness during and following vaccination roll-out in England: a retrospective, whole-country linked cohort study https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00195-1/fulltext?rss=yes

[Articles] Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00196-3/fulltext?rss=yes

[Comment] Early prevention of multimorbidity for those with severe mental illness https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00237-3/fulltext?rss=yes

[Comment] Priority is not equity: lessons from COVID-19 for people with severe mental illness https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00234-8/fulltext?rss=yes

[Correspondence] New clozapine regulations, old inequalities? https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00232-4/fulltext?rss=yes

[Comment] Beyond task sharing: the next step for global mental health https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00236-1/fulltext?rss=yes

[Articles] Optimising and personalising task-shared psychosocial interventions for common mental disorders: a Bayesian component network meta-analysis of individual participant data https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(26)00193-8/fulltext?rss=yes

A novel method to disentangle tightly linked risk and resilience genes for brain disorders: application to Alzheimer’s disease https://www.nature.com/articles/s41380-026-03814-x

Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming https://www.nature.com/articles/s41380-026-03816-9

Neuroscience in cancer care: ethical, legal, and societal challenges https://www.nature.com/articles/s41380-026-03820-z

Maternal NKG2D-mediated immune activation shapes fetal neural development https://www.nature.com/articles/s41380-026-03809-8

JAMA Psychiatry https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2852087

EEG Microstates—A Biomarker for Psychosis? https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2849802

Strategies for Establishing Clinical-Decision Thresholds in Psychiatry https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2849302

Assessing Drug Efficacy After Multiple Negative Trials https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2850581

A New CMS Payment Model for AI-Delivered Behavioral Health Care https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2850580