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147.Explanation Correct Answer - B Ans.B. Drug abuse [Ref: Niraj Ahuja ele p. 236, 237; Essentials of psychiatry 4th/e p. 734] Causes/Risk factors for suicide Psychiatric disorders: - Depression (most common), alcoholism (2nd mc), Drug/Substance dependence, Schizophrenia, Dementia. Physical illness: - Cancer, AIDS, Multiple sclerosis, Head trauma. Psychosocial factors: - Failure in love, marital difficulties, family dispute, illegitimate pregnancy. Biological factors: - Decrease in serotonin Other - Male sex, Age > 40 years, Single (Unmarried, divorced or widowed), previous suicide attempt, social isolation. Join @PSYCHIATRYhubs

147. Risk factor for suicide is?

146.Explanation Correct Answer - C Ans. C. DZd [Ref Kaplan & Saddock's 10th le p. 470] Dopamine hypothesis is the most accepted hypothesis for schizophrenia. There is hyperactivity of dopaminergic system. This hypothesis is supported by : 1. Amphetamine and cocaine which release dopamine in central synapses induce schizophrenia like symptoms; and 2. Antipsychotic drugs control the schizophrenic symptoms by blocking dopamine (D2) receptors. Join @PSYCHIATRYhubs

146. Most important receptors involved with schizophrenia are?

145.Explanation Correct Answer - C Ans. C. 6 months [Ref Harrison 17"/e p. 2712; Kaplan & Saddock's 10th/e p. 626] GENERALIZED ANXIETY DISORDER This is characterized by excessive anxiety and worry which are persistent & generalized and not restricted to any specific situation or object. Excessive anxiety worry occur for at least 6 months. Join @PSYCHIATRYhubs

145. Generalized anxiety disorder is diagnosed when anxiety and worry continues for at least?

144.Explanation Correct Answer - A Ans. A. Benzodiazepines [Ref Harrison 17th/e p. 2712; Kaplan & Saddock's 10th/e p. 626] Treatment of generalized anxiety disorder Benzodiazepines are the drug of choice. Drugs in this group are diazepam, Lorazepam, Alprazolam, Oxazepam, chlordiazepoxide. Join @PSYCHIATRYhubs

144. Treatment of choice for generalized anxiety disorder is?

143.Explanation Correct Answer - A Ans. A. Alcohol dependent syndrome [Ref Kaplan & Saddock's 10thle p. 382] Alcohol dependent syndrome Alcohol dependent syndrome uses the same criteria for dependence for other substances, i.e., three or more of the following : - 1. Tolerance 2. Withdrawal symptoms 3. Alcohol is taken in larger amount or for longer period. 4. Persistent desire or sense of compulsion to take alcohol. 5. A great deal of time spent to obtain alcohol, to use alcohol or to recover from its effect. 6. Neglect of important social, occupational and recreational activities Join @PSYCHIATRYhubs