JAMA (Journal of the American Medical Association)
описание
All the latest articles published on JAMA before going in to print Discussion Group https://t.me/Medical_Professionals_Forum Contact us https://t.me/Contact_Updates_in_Medicine_Bot
16 081
подписчиков
Охват к подписчикам
3,4%
ERR
Реакции к просмотрам
0,02%
5 на 40 постов
Пересылки к просмотрам
0,10%
21
Постов в день
4,0
всего 40
Где отзываются чаще
доля реакций к просмотрам- 17 авг.Safety of Antiseizure Medication During DOAC Therapy in Epilepsy https://jamanetwork.com/journals/jamaneurology/fullarticle/2853050 This cohort study investigates the associations between concomitant antiseizure medication selection and risks of thromboembolic events, major bleeding, and all-cause mortality among adults with epilepsy receiving direct oral anticoagulants (DOACs).0,24%
- 17 авг.A Call for Benzodiazepines in Airline Emergency Medical Kits https://jamanetwork.com/journals/jamaneurology/fullarticle/2853048 This Viewpoint discusses the importance of and considerations for including benzodiazepines in airline emergency medical kits for treating patients who experience seizure during a flight.0,22%
- 13 авг.Optimizing the Therapeutic Ratio in Prostate Radiation Therapy https://jamanetwork.com/journals/jama/fullarticle/2852853 Prostate cancer has long served as a fertile ground for innovation in cancer therapy. Compared with many other malignancies, localized prostate cancer occupies a unique clinical space. Although the incidence of new diagnoses is high, prostate cancer often follows an indolent natural history, resulting in a low risk of prostate cancer–specific mortality. Meanwhile, multiple management strategies exist, including surgery, radiation therapy, and active surveillance, which provide similar disease outcomes in appropriately selected men. As a result, treatment decisions for localized disease must account for not only oncologic outcomes but also preservation of urinary, bowel, and sexual function. Over the past several decades, advances in imaging, risk stratification (including genomics), and treatment delivery have steadily reshaped prostate cancer care with a common goal: in men with early-stage disease who receive local therapy, clinicians and investigators must attempt to optimize the therapeutic ratio by maintaining high rates of cancer control, while minimizing treatment-related morbidity.0,21%
- 12 авг.A Review of Endometrial Cancer https://jamanetwork.com/journals/jama/fullarticle/2852744 To the Editor A recent Review offered a comprehensive overview of endometrial cancer, highlighting the emerging significance of molecular classification in informing prognosis and treatment, which reflects the growing role of molecular classification in clinical care. Nevertheless, the practical implementation of molecular classification was inadequately explored. Access to comprehensive molecular testing is inconsistent across health care systems. Even in high-resource settings, the availability of assays such as polymerase epsilon (POLE) sequencing is variable and result interpretation lacks standardization. These challenges are more pronounced in low-resource settings, resulting in a disparity between theoretical optimal care and real-world clinical practice.0,15%
- 13 авг.Focal Therapy for Prostate Cancer https://jamanetwork.com/journals/jama/fullarticle/2852850 This retrospective study uses data from the National Cancer Database to examine patterns and temporal trends in use of focal therapy for prostate cancer in US cancer centers; characterize inappropriate use in low-, high-, or very–high-risk disease; and describe intermediate-risk use.0,14%
- 17 авг.Anti-CD320 Autoantibodies and CNS Vitamin B 12 Deficiency in Idiopathic Myelopathy https://jamanetwork.com/journals/jamaneurology/fullarticle/2853049 This case-control study reports on a novel antibody associated with idiopathic myelopathy.0,00%
- 17 авг.Suicide Mortality After Launch of a Suicide and Crisis Lifeline https://jamanetwork.com/journals/jama/fullarticle/2852955 To the Editor Dr Patel and colleagues’ recent article provides promising evidence that the 988 Suicide and Crisis Lifeline has been successful at preventing suicide death. Indeed, their results comparing “high-uptake” and “low-uptake” states are consistent with a time series analysis of pre–988 Lifeline data that found that daily increases in call volume were associated with daily decreases in suicide deaths. However, the precision of Patel and colleagues’ estimates could be enhanced by accounting for between-state heterogeneity in 988 Lifeline implementation and relevant state-level contextual factors.0,00%
- 17 авг.Suicide Mortality After Launch of a Suicide and Crisis Lifeline https://jamanetwork.com/journals/jama/fullarticle/2852956 To the Editor Dr Patel and colleagues report that the national launch of the 988 Suicide and Crisis Lifeline was associated with an 11% reduction in adolescent and young adult suicide deaths (4372 fewer than expected). These findings suggest that a phone-based open-access crisis service achieved what the traditional health care system seldom does—population-level reductions in mortality. Missing from the authors’ discussion is the close connection between suicide and substance use disorders, particularly opioid use disorder (OUD). Suicidal ideation is highly prevalent (25%-40%) in OUD, and the distinction between opioid-related risk taking and suicidality is often clinically ambiguous. In the year after an emergency department visit for nonfatal opioid overdose, survivors experienced 282 excess suicide deaths per 100 000 persons vs a demographically matched general population—an 18-fold increase in risk. National Center for Health Statistics data show that unintentional drug overdose deaths outnumber suicide deaths in the age cohort studied by Patel and colleagues. The authors’ outcome definition excludes unintentional and undetermined-intent drug poisonings (International Classification of Diseases and Related Health Problems, Tenth Revision codes X40-X44 and Y10-Y14), which likely include many unrecognized suicide deaths (more than 20% in one study).0,00%
- 17 авг.A World With Platelets Stored Cold for 21 Days https://jamanetwork.com/journals/jama/fullarticle/2852958 A platelet transfusion is a small miracle. To get the platelets, a supplier must find donors who will volunteer to spend 2 hours undergoing apheresis. Every platelet unit donated needs complex bacterial testing or expensive pathogen reduction followed by continuous agitation in a thermally controlled shaker at room temperature. After all this, the platelets have a shelf life of only 5 to 7 days, and because the testing takes up most of the first 2 days, the usable window is only 3 to 5 days long. Platelets are fragile, expensive, and perpetually in short supply.0,00%
- 17 авг.Vaccine Policy in the Face of Low Hepatitis B Immunity https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2852506 Despite the availability of hepatitis A and B vaccinations, a rise in hepatitis A outbreaks and minimal progress in hepatitis B prevention efforts necessitated a collaborative, strategic approach to eliminating hepatitis infection in the US. The Viral Hepatitis—National Strategic Plan: A Roadmap to Elimination for the United States (2021-2025), spearheaded by the US Department of Health and Human Services, was published in 2020 as a framework to achieve this goal, defined by the World Health Organization as a 90% reduction in new chronic infections and a 65% reduction in mortality.0,00%
- 17 авг.Reframing the Approach to High-Risk Electrocardiography Patterns https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2852507 This case report describes the electrocardiogram findings of a patient in their 40s with dizziness and presyncope after hematemesis and multiple black stools.0,00%
- 14 авг.Drinking Water Contaminants Associated With Uterine Cancer Risk https://jamanetwork.com/journals/jama/fullarticle/2853041 Common public drinking water contaminants may be linked to an increased risk of uterine cancer, a study published in JAMA Network Open found.0,00%